Barrymore is a surname. Notable people with the surname include:
Barrymore family of American actors Earl of Barrymore, a title in the Kingdom of Ireland dating to 1622
People with the surname Barrymore Deborah Barrymore aka Deborah Moore (born 1963), English actress Diana Barrymore (1921–1960), American actress Drew Barrymore (born 1975), American actress and producer Ethel Barrymore (1879–1959), American actress John Barrymore (1882–1942), American actor John Drew Barrymore (1932–2004), also known as John Barrymore Jr., actor Lionel Barrymore (1878–1954), American actor Maurice Barrymore (1849–1905), forefather of the Barrymore family of American actors Michael Barrymore (born 1952), English comedian
Fictional people with the surname Barrymore Mr. & Mrs. Barrymore, characters of the novel The Hound of the Baskervilles
See also Barony of Barrymore, a barony in County Cork, Ireland Barrymore (play), a one-man show starring Christopher Plummer and written by William Luce Barrymore (film), 2011 film adaptation of the play Barrymore (TV series), a TV show hosted by Michael Barrymore Barrymore's, a nightclub in Ottawa, Ontario