Jeaffreson is a given name and a surname. Notable people with the name include:
Jeaffreson Vennor Brewer (1853–1924), rugby union international, represented England in 1875 Jeaffreson Greswell (1916–2000), British pilot during the Second World War Edward Jeaffreson Jackson (born 1862), Australian architect in the Arts and Crafts style David Jeaffreson, CBE, JP (1931–2008), British colonial government official and civil servant John Cordy Jeaffreson (1831–1901), English novelist and author of popular non-fiction
See also Geferson Jefferson (disambiguation)