Ohayon is a surname. Notable people with the surname include:
Almog Ohayon (born 1994), Israeli footballer Amandine Ohayon, CEO of Pronovias, a wedding dress design business in Spain Ayelet Ohayon (born 1974), three-time Olympian Israeli foil fencer Haviv Ohayon (born 1998), Israeli footballer Henry Ohayon (1934–2023), Israeli cyclist Jonathan Ohayon (born 1972), athlete from Canada, grandson of writer Joseph Liss Matan Ohayon, retired Israeli footballer Michèle Ohayon (born 1968), film director, screenwriter and producer Moshe Ohayon (born 1983), Israeli former professional football midfielder Shimon Ohayon (born 1945), Israeli politician, professor at Bar-Ilan University Yogev Ohayon (born 1987), Israeli professional basketball player