Soisson is a surname. Notable people with the surname include:

Gérard Soisson (1935–1983), Luxembourgish banker at the center of the Clearstream Affair Guillaume Soisson (1866–1938), Luxembourgian engineer and politician Jacques Soisson (1928–2012), French artist, child and adolescent psychotherapist Jean-Pierre Soisson (born 1934), French politician Joel Soisson, American screenwriter, producer and director Renaud III, Count of Soisson (died 1141), French aristocrat

See also Soisson-Rapacz-Clason Field, a multipurpose stadium in Kalamazoo, Michigan, US Soissons