Angelique Kerber defeated Kaja Juvan in the final, 7–6(7–5), 6–7(0–7), 7–6(7–5) to win the singles tennis title at the 2022 Internationaux de Strasbourg. It was her 14th WTA Tour singles title. The final lasted three hours and 20 minutes.
Barbora Krejčíková was the reigning champion, but withdrew before the tournament.
This was Samantha Stosur's final professional appearance in singles; she lost in the first round to Harmony Tan.
Seeds
Draw
Finals
Top half
Bottom half
Qualifying Seeds
Qualifiers
Lucky losers
Qualifying draw First qualifier
Second qualifier
Third qualifier
Fourth qualifier
References
Main draw Qualifying draw