C2C may stand for:

Transport c2c, an English train operating company c2c (1996–2025), a former English train operating company Sea to Sea Cycle Route, a bicycle route in England Coast-to-Coast Trail, a multi-use path in Florida currently under construction

Entertainment C2C (group), French DJ group C2C (studio), a Japanese animation studio C2C: Country to Country, a country music festival in London Cover to Cover tour, a 1991 tour by George Michael Coast to Coast AM, a syndicated AM talk radio show

Technology C2C (cable system), linking east Asia and the United States Click-to-call, a web technology to immediately initiate calls to another person Consumer-to-consumer, electronic transactions between consumers through a third party Cradle-to-cradle design, a biomimetic approach to the design of products

Other Coast to Coast Athletic Conference, a US college athletic conference Copy to China, when a Chinese company copies the business model of a successful foreign company