Sam Kirk (born 1981; as Samantha Kirk) is an American artist.
Sam, Samuel or Samantha Kirk may also refer to:
People Samuel Kirk (psychologist) (1904–1996), American psychologist Samuel Kirk (silversmith) (1793–1872), American silversmith Tom Kirk (rugby league) (1916–1994; born Albert Samuel Kirk), Australian rugby league player Robert Samuel Kirk, honoured at the British 2019 Birthday Honours
Fictional characters George Samuel Kirk, Jr. (Star Trek), older brother of James T. Kirk, known as "Sam" George Samuel Kirk, Sr. (Star Trek), father of James T. Kirk and Sam Kirk
Other uses Samuel Kirk & Sons; a U.S. silverware company established by Samuel Kirk (silversmith)