Morfin or Morfín is a surname. Notable people with the surname include:
Carlos Morfín (born 1949), Mexican water polo player Jesús Flores Morfín (born 1953), Mexican politician José González Morfin (born 1954), Mexican politician and lawyer Lorenza Morfín (born 1982), Mexican road cyclist
Fictional characters Morfin Gaunt, a Harry Potter character Mr Morfin, in Dombey and Son