Luthe or Lüthe is a German language surname. It stems from the male given name Ludwig – and may refer to: Andreas Luthe (1987), German professional footballer Claus Luthe (1932–2008), German car designer Gregor Luthe (1970), German chemist, toxicologist, nanotechnologist, inventor and entrepreneur Hubert Luthe (1927–2014), German Catholic bishop Josephine M. Luthe (19th-century), American lawyer Wolfgang Luthe (1922–1985), German physician and psychotherapist

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