Reina Mercedes refers to several topics:
"Reina Mercedes" is Spanish for "Queen Mercedes," and refers to Mercedes of Orleans, Queen Consort of Spain, wife of Alfonso XII. Reina Mercedes was a Spanish cruiser that fought in the Spanish–American War. USS Reina Mercedes was a ship in the United States Navy. Reina Mercedes is a municipality in the Philippines. Reina Mercedes Hospital, demolished to build the Cuban ice cream parlour Coppelia