Pasqualino is a surname and given name. Notable people with the name include:
surname Antonio Pasqualino, 15th-century Patrician of Venice Fortunato Pasqualino, Italian novelist, philosopher, playwright and journalist Luke Pasqualino (born 1990), British actor
given name Pasqualino Abeti (born 1948), Italian sprinter Pasqualino Borsellino (born 1956), Italian football player and manager Pasqualino De Santis (1927–1996), Italian cinematographer Pasqualino Lolordo (1887–1929), was an Italian-born American Mafia boss Pasqualino Morbidelli (1948–2020), Italian boxer Pasqualino Moretti (born 1947), Italian cyclist