Mary Ellen is a given name. Notable people with the name include:
Mary Ellen Duncan (1941–2022), American academic administrator and teacher Mary Ellen Mark (1940–2015), American photographer Mary Ellen Pleasant (1815–1904), American entrepreneur, financier, real estate magnate, and abolitionist Mary Ellen Powers, birth name of Mala Powers (1931–2007), American actress Mary Ellen Swan (1892–2004), Canadian supercentenarian Mary Ellen Turpel-Lafond (born 1963), Canadian lawyer, former judge, and legislative advocate for children's rights Mary Ellen Wilson (1864–1956), American child abuse victim