IHCH-7113 is a serotonin 5-HT2A receptor agonist and serotonergic psychedelic of the pyridopyrroloquinoxaline family. It was derived by structural simplification of the serotonin 5-HT2A receptor antagonist and atypical antipsychotic lumateperone. Other related compounds include IHCH-7079 and IHCH-7086, which were found to be non-hallucinogenic biased serotonin 5-HT2A receptor agonists that were active in antidepressant assays but did not produce psychedelic-like responding in mice. IHCH-7113 on the other hand produced a head-twitch response comparable to that of DOI or LSD, which was blocked by the serotonin 5-HT2A receptor antagonist volinanserin.Robichaud AJ, et al. Substituted heterocycle fused gamma-carbolines. Patent US 6552017Tomesch JC, et al. Preparation of 4-((6BR,10AS)-3-methyl-2,3,6B,9,10, 10A-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo [1,2,3-de]quinoxalin-8-(7H)-yl)-1-(4-fluorophenyl)-1-butanone or a pharmaceutically acceptable salt thereof. Patent US 9315504 The drug is not a controlled substance in the United States or Canada.
See also Pyridopyrroloquinoxaline Substituted γ-carboline WAY-163909
References
External links IHCH-7113 - Am I possibly the first person who tried it? + with report - r/researchchemicals - Reddit [Comment] - Are there any potentially new psychedelic classes out there? - r/researchchemicals/ - Reddit