David Mark Haddleton (born 1962) is a professor in the department of chemistry at The University of Warwick. Haddleton’s work focuses on controlled polymer synthesis and the industrial applications of polymer materials. He is a Fellow of the Royal Society of Chemistry.
Career Haddleton was editor in chief of the European Polymer Journal from 2002 – 2009 prior to becoming the founding editor and editor in chief of the Royal Society of Chemistry Polymer Chemistry from 2009 to 2017.https://pubs.rsc.org/en/journals/journalissues/py He sat on the Royal Society of Chemistry publishing board between 2017 and 2023. He is the executive editor in chief of Cambridge Materials journals published by Cambridge University Press (CUP). His research has been closely aligned with a number of companies, including Unilever, Lubrizol and Syngenta. He has founded two companies Warwick Effect Polymers Ltd (now part of Abzena) a drug-polymer conjugation company and Medherant Ltd which develops transdermal drug delivery patches for delivery of testosterone for womenhttps://www.nature.com/articles/d43747-025-00012-6 where he is a director and CSO. He has been an adjunct professor at Monash University in both the Departments of Materials Engineering and Pharmacy since 2013 and has been a Chair Professor at Soochow University in Suzhou, China.
Selected publications
Ladmiral, V.; Mantovani, G.; Clarkson, G. J.; Cauet, S.; Irwin, J. L.; Haddleton, D. M., Synthesis of neoglycopolymers by a combination of "click chemistry" and living radical polymerization. Journal of the American Chemical Society 2006, 128 (14), 4823-4830. https://doi.org/10.1021/ja058364k Mantovani, G.; Lecolley, F.; Tao, L.; Haddleton, D. M.; Clerx, J.; Cornelissen, J.; Velonia, K., Design and synthesis of N-maleimido-functionalized hydrophilic polymers via copper-mediated living radical polymerization: A suitable alternative to PEGylation chemistry. Journal of the American Chemical Society 2005, 127 (9), 2966-2973. https://doi.org/10.1021/ja0430999 Ryan, S. M.; Mantovani, G.; Wang, X. X.; Haddleton, D. M.; Brayden, D. J., Advances in PEGylation of important biotech molecules: delivery aspects. Expert Opinion on Drug Delivery 2008, 5 (4), 371-383. https://doi.org/10.1517/17425247.5.4.371 Tao, L.; Mantovani, G.; Lecolley, F.; Haddleton, D. M., α-Aldehyde terminally functional methacrylic polymers from living radical polymerization: Application in protein conjugation "pegylation". Journal of the American Chemical Society 2004, 126 (41), 13220-13221. https://doi.org/10.1021/ja0456454 Zhang, Q.; Wilson, P.; Li, Z. D.; McHale, R.; Godfrey, J.; Anastasaki, A.; Waldron, C.; Haddleton, D. M., Aqueous Copper-Mediated Living Polymerization: Exploiting Rapid Disproportionation of CuBr with Me6TREN. Journal of the American Chemical Society 2013, 135 (19), 7355-7363. https://doi.org/10.1021/ja4026402 Haddleton, D. M.; Jasieczek, C. B.; Hannon, M. J.; Shooter, A. J., Atom transfer radical polymerization of methyl methacrylate initiated by alkyl bromide and 2-pyridinecarbaldehyde imine copper(I) complexes. Macromolecules 1997, 30 (7), 2190-2193. https://doi.org/10.1021/ma961074r Anastasaki, A.; Nikolaou, V.; Nurumbetov, G.; Wilson, P.; Kempe, K.; Quinn, J. F.; Davis, T. P.; Whittaker, M. R.; Haddleton, D. M., Cu(0)-Mediated Living Radical Polymerization: A Versatile Tool for Materials Synthesis. Chemical Reviews 2016, 116 (3), 835-877. https://doi.org/10.1021/acs.chemrev.5b00191 Davis, T. P.; Kukulj, D.; Haddleton, D. M.; Maloney, D. R., Cobalt-Mediated Free-Radical Polymerisation of Acrylic-Monomers. Trends in Polymer Science 1995, 3 (11), 365-373. https://www.scopus.com/record/display.uri?eid=2-s2.0-0001042297&origin=inward&txGid=a854b72ffb71b1d10ed6a7e96b904cca Engelis, N. G.; Anastasaki, A.; Nurumbetov, G.; Truong, N. P.; Nikolaou, V.; Shegiwal, A.; Whittaker, M. R.; Davis, T. P.; Haddleton, D. M., Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization. Nature Chemistry 2017, 9 (2), 171-178. https://doi.org/10.1038/nchem.2634
External links
David Haddleton’s Warwick University homepage David Haddleton publications indexed by Google Scholar
References