Szeptycki (feminine: Szeptycka) is a Polish-language surname. It belongs to the Polish noble Szeptycki family. The Ukrainian-language spelling of the surname is Sheptytskyi (; feminine: Sheptytska). The name is also sometimes rendered as Sheptytsky or Sheptycki. Notable people with the surname include:

Szeptycki, Szeptycka Athanasius Szeptycki (1686–1746), bishop Jadwiga Szeptycka (1883–1939), Polish archeologist, ethnographer, writer and social activist James Sheptycki, Canadian criminologist Kamil Szeptycki (born 1991), Polish actor Leo Szeptycki (1717–1779), bishop Stanisław Szeptycki (1867–1950), Polish general and minister Zofia Szeptycka (1837–1904), Polish countess, poet and painter

Sheptytsky, Sheptytskyi Andrey Sheptytsky (1865–1944), Metropolitan Archbishop of the Ukrainian Greek Catholic Church Klymentiy Sheptytsky (1869–1951), archimandrite of the Ukrainian Greek Catholic Church Oleh Sheptytskyi (born 1986), Ukrainian footballer

See also Sheptytskyi, a city in Ukraine