William Nicholas may refer to:
William Nicholas (officer) (1785–1812), English officer in the British Army William H. Nicholas (1892–1984), American politician who served twice as the Lieutenant Governor of Iowa
See also
William Nicholas Darnell (1776–1865), English cleric, academic and antiquarian William Nicholas Searancke (1817–1904), New Zealand surveyor, land purchase commissioner, resident magistrate and land agent William Nicholas Keogh (1817–1878), Irish politician and judge William Nicholas Hailmann (1836-1920), American educator William Nicholas Selig (1864–1948), American film pioneer William Nicholas Willis (1858–1922), Australian politician William Nicholas Stone Courtney (1929–2011), British actor William Nicholas Straub House, historic house in Arkansas