Thiophene-2-acetic acid is the organosulfur compound with the formula HO2CCH2C4H3S. Together with thiophene-3-acetic acid, it is one of two isomeric thiophene acetic acids.

Preparation and use It is prepared from 2-acetylthiophene.

It is a precursor to the antibiotics cephaloridine and cephalothin..

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