Wetzell is a surname. Notable people with the surname include:
Georg Wetzell (1869–1947), German military officer Oskar Wetzell (1888–1928), Finnish Olympic diver Pippa Wetzell (born 1977), New Zealand television personality and journalist Richard Wetzell (born 1961), American historian Stig Wetzell (born 1945), Finnish ice hockey player Yanni Wetzell (born 1996), New Zealand basketball player
See also Wetzell-Archbold Farmstead, historic farmhouse in Washington, D.C. Zebediah F. and Mary H. Wetzell House, historic residence in St. Louis, Missouri Wetzel (disambiguation)