General Wharton may refer to:
Gabriel C. Wharton (1824–1906), Confederate States Army brigadier general James Edward Wharton (1894–1944), U.S. Army brigadier general John A. Wharton (1828–1865), Confederate States Army major general John F. Wharton (general) (born c. 1957), United States Army major general Robert Wharton (Philadelphia) (1757–1834), Pennsylvania Militia brigadier general