Lopo may refer to:
People Surname Alberto Lopo (born 1980), Spanish football player Fausto Lopo de Carvalho, Portuguese pulmonologist Santiago Lopo (born 1974), Galician author Given name Lopo Fernandes Pacheco (died 1349) Lopo Gomes de Abreu (1420–70s?), Portuguese nobleman Lopo Homem (16th century), Portuguese cartographer and cosmographer Lopo Soares de Albergaria Lopo Vaz de Sampaio Lopo de Almeida (1416–1486) Lopo de Alpoim (1400-?), Portuguese nobleman Lopo de Brito Lopo do Nascimento (born 1942), Angolan politician
Other Lopo house LOPO, meaning low power, the first aqueous homogeneous reactor