William Sanford may refer to: William Eli Sanford (1838–1899), Canadian businessman, philanthropist, and politician William Ayshford Sanford (1818–1902), Australian landowner, naturalist and politician William Taylor Barnes Sanford (1814–1863), American road builder and member of the Los Angeles council
See also William Sandford (1841–1932), English-Australian ironmaster William Sandford (colonist) (1637–1691), colonist, planter, government official and militiaman.