The 1959 Little All-America college football team is composed of college football players from small colleges and universities who were selected by the Associated Press (AP) as the best players at each position. For 1959, the AP selected three teams of 11 players each, with no separate defensive platoons.

Quarterback Sam McCord from East Texas passed for 559 yards and 13 touchdowns, rushed for 887 yards, handled punting, and was also the team's best defensive back with four interceptions.

Walt Beach of Central Michigan had 542 rushing yards, 222 receiving yards, and 522 yards on kick returns, and scored 88 points.

Bill Larson led Western Illinois to a perfect 9–0 record, rushing for 890 yards and scoring 76 points.

Vince Tesone of Colorado Mines passed for 1,619 yards, rushed for 492 yards and seven touchdowns, and punted for an average of 42.2 yards.

Center Roger LeClerc made 50 percent of the tackles for Trinity (Connecticut), intercepted five passes (returning two for touchdowns), and also handled punting and place-kicking. He later played eight years in the NFL.

First team Position Player Team B Sam McCord East Texas Walt Beach Central Michigan Vince Tesone Colorado Mines Bill Larson Western Illinois E Hugh McInnis Mississippi Southern Tom Hackler Tennessee Tech T Walt Meineke Lehigh Bob Zimpfer Bowling Green G Gerald Lambert Texas A&I Marvin Cisneros Willamette C Roger LeClerc Trinity (CT)

Second team Position Player Team B Jim Sochor San Francisco Henry Hawk Arkansas State Bill Berrier Juniata Jack Turner Delaware E John Simko Augustana (SD) Brady Luckett Middle Tennessee T Bill Beck Gustavus Adolphus Jim Larkin Hillsdale G George Dempster Hofstra Clarence Cheatham Western Michigan C Curtis Miranda Florida A&M

Third team Position Player Team B Lee Farmer Lenoir–Rhyne Bill Shockley West Chester Dale Mills Kirksville State Brad Hustad Luther George Phelps Cornell (IA) E Al Badger Southern Connecticut Bill Wiljanen Michigan Tech T Walt Stockslager Butler Jim Pater Coe G Garvin Boggs Chico State Bill Odden Presbyterian C Rich Max Cal Poly

See also 1959 College Football All-America Team

References