A tetralogy is a set of four dramatic or literary works.

Tetralogy may also refer to: Ingo tetralogy, a series of children's novels by author Helen Dunmore. Ware Tetralogy, a series of science fiction novels by author Rudy Rucker Tetralogy (album), an album by trombonist Paul Rutherford Tetralogy of Fallot, a congenital heart defect