The 2021–22 Pittsburgh Panthers women's basketball team represented the University of Pittsburgh during the 2021–22 NCAA Division I women's basketball season. The Panthers, led by fourth-year head coach Lance White, played their home games at the Petersen Events Center as members of the Atlantic Coast Conference.

The Panthers finished the season 11–19 overall, and 2–16 in ACC play, to finish in a tie for fourteenth place. As the fifteenth seed in the ACC tournament, they lost their First Round matchup with Duke. They were not invited to the NCAA tournament or the WNIT.

Previous season

The Panthers finished the season 5–14 and 3–12 in ACC play to finish in twelfth place. In the ACC tournament, they lost to Boston College in the first round. They were not invited to the NCAA tournament or the WNIT.

Off-season

Departures

Departures Cara Judkins 11 C 6'2" Senior Bethesda, MD Graduated Gabbie Green 12 G 5'7" Senior Bellville, TX Transferred to Louisiana Tech Marcella LaMark 21 C 6'4" Senior São Paulo, Brazil Graduated

Incoming transfers

Incoming transfers Mary Dunn 15 F 6'3" Graduate student Washington, PA Youngstown State

Recruiting class

Source:

Roster

Schedule

Source:

!colspan=6 style=| Regular season

!colspan=6 style=| ACC Women's tournament

Rankings

+ Regular season pollsPoll Pre-season Week2 Week3 Week4 Week5 Week6 Week7 Week8 Week9 Week10 Week11 Week12 Week13 Week14 Week15 Week16 Week17 Week18 Final AP Coaches + Legend   Increase in ranking   Decrease in ranking   Not ranked in previous week (RV)   Received votes (NR)   Not ranked

Coaches did not release a Week 2 poll, and AP does not release a poll after the NCAA tournament.

References