Deportivo Cali is a professional football club based in Cali, Colombia, which plays in Categoría Primera A. This chronological list comprises all those who have held the position of manager of the first team of Deportivo Cali since 1912, the date of the first available data for a club manager. Each manager's entry includes his years of tenure, honours won and significant achievements while under his care, where available. Caretaker managers and player-managers are included, where known. As of 2026, Deportivo Cali has had 57 known full-time managers, 10 caretaker managers, and 5 player-managers.

The first known manager for Deportivo Cali in the professional era was Moisés Emilio Reuben, who arrived to the club as a player in 1947 and was appointed as player-manager shortly after, ahead of the team's first participation in the Colombian football championship in 1948.

The most successful Deportivo Cali manager in terms of trophies won is Francisco "Pancho" Villegas, who won three Categoría Primera A trophies in his first five-year tenure as manager. He is also the club's longest-serving manager, having served for five years between 1965 and 1970 and then again for a brief period in 1976.

List of managers The complete list of Deportivo Cali managers is shown in the following table:

Italics denote a caretaker manager, PM denotes a player-manager.

NameFromToHonoursFrancisco Villa Bisa19121912Moisés Emilio ReubenPM19471948Adelfo Magallanes19491949Carlos Peucelle19501950Manuel GiúdicePM19501951Roberto Scarone19511952Julio Tocker19531953Camilo CervinoPM19541954Pablo Rojas19541954Santiago RivasPM19551955Julio Tocker19591959Manuel SanguinettiPM19591959José Fabrini19601960Carlos Peucelle19611961Luis López19611962Gaudencio Thiago de Melo19631963Óscar Ramos19631964Francisco Solano Patiño19641964Francisco "Pancho" Villegas196519703 Categoría Primera AFederico Vairo19661966Roberto Resquín197019711 Categoría Primera ALuis López19711971Óscar López19711972Vladislao Cap19721973Vladimir Popović197419741 Categoría Primera ARaúl Rodríguez Seaone19751975Washington Etchamendi19761976Jorge Ramírez Gallego19761976Néstor Rossi19761976Francisco "Pancho" Villegas19761976Carlos Bilardo19761978Eduardo Luján Manera19791980Edilberto Righi19801981Miguel Ángel Basílico19821982Eduardo Retat19831983Pedro Nel Ospina19841984Vladimir Popović19841986Julio Comesaña19861987Óscar Tabárez19881988Carlos Portela19881988Vladimir Popović19891989Jorge Luis Pinto19901991Miguel Company19911992Carlos Portela19931993José Yudica19931994Fernando Castro199519971 Categoría Primera AReinaldo Rueda19971998José Eugenio Hernández199820001 Categoría Primera ALuis Fernando Suárez20012001Néstor Otero20012001Fernando Castro20022002Óscar Quintabani20022003Sergio Angulo20032003Javier Álvarez20032003Bernardo Redín20042004Norberto Peluffo20042004Jaime de la Pava20052005Pedro Sarmiento200520061 Categoría Primera AOmar Labruna20062007Néstor Otero20072007Daniel Carreño20082008Ricardo Martínez20082008José Eugenio Hernández20092009Jorge Luis Bernal20102010Jorge Cruz20102010Jaime de la Pava201020111 Copa ColombiaJorge Cruz20112011Jairo Arboleda20112011Rubén Darío Insúa20112012Julio Comesaña20122012Héctor Cárdenas20122012Leonel Álvarez201320141 Superliga ColombianaHéctor Cárdenas20142014Fernando Castro201520161 Categoría Primera AMario Yepes20162017Héctor Cárdenas20172017Sergio Angulo20172017Gerardo Pelusso20182018Lucas Pusineri20192019Alfredo Arias20202021Ítalo Cervino20212021Rafael Dudamel202120221 Categoría Primera AÍtalo Cervino20222022Mayer Candelo20222022Sergio Angulo20222022Jorge Luis Pinto20222023Sergio Herrera20232023Jaime de la Pava20232024Hernando Patiño20242024Hernán Torres20242024Sergio Herrera20242024Alfredo Arias20252025Sergio Herrera20252025Alberto Gamero20252026Rafael Dudamel2026

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