Marsicano is a surname. Notable people with the surname include:
Alberto Marsicano (1952–2013), Brazilian musician, translator, writer, philosopher and professor Merle Marsicano (1903–1983), American dancer and choreographer Michael Marsicano (born 1956), American entrepreneur, President and CEO of Foundation For The Carolinas Nicholas Marsicano (1908–1991), American painter and university teacher Trevor Marsicano (born 1989), American speed skater and Olympian Claudia Marsicano (born 1992), Italian actress