The 2022 San Diego Padres season was the 54th season of the San Diego Padres franchise. The Padres play their home games at Petco Park as members of Major League Baseball's (MLB) National League West.

On December 2, 2021, Commissioner of Baseball Rob Manfred announced a lockout of players, following expiration of the collective bargaining agreement (CBA) between the league and the Major League Baseball Players Association (MLBPA). On March 10, 2022, MLB and the MLBPA agreed to a new collective bargaining agreement, thus ending the lockout. Opening Day was played on April 7. Although MLB previously announced that several series would be cancelled due to the lockout, the agreement provides for a 162-game season, with originally canceled games to be made up via doubleheaders.

On October 2, San Diego clinched their first wild card berth since the pandemic shortened 2020 season and their first in a full season since the 2006 season. They defeated the New York Mets in the NLWCS and the Los Angeles Dodgers in the NLDS. The Padres' 3–1 victory over the Dodgers was considered a historic upset, as their 111 wins in the regular season were the fourth most in MLB history and 22 more than San Diego's 89. The only time in league playoff history that a team defeated an opponent who was more than 22 wins better was in the 1906 World Series, when the 93-win Chicago White Sox defeated the 116-win Chicago Cubs. San Diego advanced to face Philadelphia Phillies in the NLCS, the Padres' first championship series since 1998. However, they were defeated by the Phillies, losing in five games.

Offseason Lockout

The expiration of the league's collective bargaining agreement (CBA) with the Major League Baseball Players Association occurred on December 1, 2021, with no new agreement in place. As a result, the team owners voted unanimously to lockout the players stopping all free agency and trades.

The parties came to an agreement on a new CBA on March 10, 2022.

Rule changes Pursuant to the new CBA, several new rules were instituted for the 2022 season. The National League adopted the designated hitter full-time, a draft lottery was implemented, the postseason will expand from ten teams to twelve, and advertising patches appeared on player uniforms and helmets for the first time.

Acquisitions PositionPlayer2021 TeamRefRPNick MartinezFukuoka SoftBank HawksRPRobert SuarezHanshin TigersCJorge AlfaroMiami MarlinsDHLuke VoitNew York YankeesSPSean ManaeaOakland AthleticsRPLuis GarcíaSt. Louis CardinalsOFNomar MazaraDetroit TigersCPTaylor RogersMinnesota TwinsOFTrayce ThompsonChicago CubsRPRay KerrSeattle MarinersOF/1BBrent RookerMinnesota TwinsOF/1BMatt BeatyLos Angeles DodgersUTLBrandon DixonTohoku Rakuten Golden EaglesRPTayler ScottHiroshima Toyo Carp

Departures PositionPlayer2022 TeamRefCPMark MelanconArizona DiamondbacksOFTommy PhamCincinnati RedsIFAdam FrazierSeattle MarinersRPMatt StrahmBoston Red SoxSPChris PaddackMinnesota TwinsCVictor CaratiniMilwaukee BrewersRPDaniel HudsonLos Angeles DodgersSPJake ArrietaRetiredRPEmilio PaganMinnesota TwinsOFJake MarisnickTexas RangersRPMiguel DíazDetroit TigersRPKeone KelaTokyo Yakult SwallowsOFBrian O'GradySaitama Seibu LionsRPNick RamirezSeattle MarinersOFPatrick KivlehanChicago White SoxSPVince VelasquezChicago White SoxOFJohn AndreoliPhiladelphia PhilliesRPRoss DetwilerCincinnati Reds

Regular season

Season standings

National League West

National League Wild Card

Record vs. opponents

Game log Regular season

|- style="background:#fbb;" | 1 || April 7 || @ Diamondbacks || 2–4 || Mantiply (1–0) || Suárez (0–1) || — || 35,508 || 0–1 || L1 |- style="background:#bfb;" | 2 || April 8 || @ Diamondbacks || 3–0 || Manaea (1–0) || Pérez (0–1) || Rogers (1) || 17,297 || 1–1 || W1 |- style="background:#bfb;" | 3 || April 9 || @ Diamondbacks || 5–2 || Wilson (1–0) || Kennedy (0–1) || Rogers (2) || 19,504 || 2–1 || W2 |- style="background:#bfb;" | 4 || April 10 || @ Diamondbacks || 10–5 || Adams (1–0) || Smith (0–1) || — || 19,089 || 3–1 || W3 |- style="background:#bfb;" | 5 || April 11 || @ Giants || 4–2 || Wilson (2–0) || Rogers (0–1) || Rogers (3) || 23,279 || 4–1 || W4 |- style="background:#fbb;" | 6 || April 12 || @ Giants || 2–13 || Cobb (1–0) || Darvish (0–1) || — || 25,560 || 4–2 || L1 |- style="background:#fbb;" | 7 || April 13 || @ Giants || 1–2 || Webb (1–0) || Manaea (1–1) || Doval (1) || 27,197 || 4–3 || L2 |- style="background:#bfb;" | 8 || April 14 || Braves || 12–1 || Musgrove (1–0) || Morton (1–1) || — || 44,844 || 5–3 || W1 |- style="background:#fbb;" | 9 || April 15 || Braves || 2–5 || O'Day (1–0) || Johnson (0–1) || Jansen (1) || 41,993 || 5–4 || L1 |- style="background:#fbb;" | 10 || April 16 || Braves || 2–5 || Anderson (1–1) || Martinez (0–1) || Jansen (2) || 36,924 || 5–5 || L2 |- style="background:#bfb;" | 11 || April 17 || Braves || 2–1 || Darvish (1–1) || Elder (1–1) || Rogers (4) || 37,694 || 6–5 || W1 |- style="background:#bfb;" | 12 || April 18 || Reds || 4–1 || Manaea (2–1) || Lodolo (0–2) || Rogers (5) || 31,121 || 7–5 || W2 |- style="background:#bfb;" | 13 || April 19 || Reds || 6–2 || Musgrove (2–0) || Sanmartin (0–2) || — || 31,313 || 8–5 || W3 |- style="background:#bfb;" | 14 || April 20 || Reds || 6–0 || Gore (1–0) || Gutiérrez (0–3) || — || 29,359 || 9–5 || W4 |- style="background:#fbb;" | 15 || April 22 || Dodgers || 1–6 || Urías (1–1) || Martinez (0–2) || — || 44,482 || 9–6 || L1 |- style="background:#bfb;" | 16 || April 23 || Dodgers || 3–2 || Suárez (1–1) || Bruihl (0–1) || — || 44,444 || 10–6 || W1 |- style="background:#fbb;" | 17 || April 24 || Dodgers || 2–10 || Kershaw (3–0) || Manaea (2–2) || — || 44,930 || 10–7 || L1 |- style="background:#bfb;" | 18 || April 26 || @ Reds || 9–6 || Musgrove (3–0) || Sanmartin (0–3) || - || 10,056 || 11–7 || W1 |- style="background:#bfb;" | 19 || April 27 || @ Reds || 8–5 || Gore (2–0) || Gutiérrez (0–4) || Rogers (6) || 9,192 || 12–7 || W2 |- style="background:#bfb;" | 20 || April 28 || @ Reds || 7–5 || Martinez (1–2) || Mahle (1–3) || Rogers (7) || 10,449 || 13–7 || W3 |- style="background:#bfb;" | 21 || April 29 || @ Pirates || 7–3 || Darvish (2–1) || Thompson (0–3) || — || 9,755 || 14–7 || W4 |- style="background:#fbb;" | 22 || April 30 || @ Pirates || 6–7 || Stratton (1–1) || García (0–1) || — || 20,483 || 14–8 || L1

|- style="background:#bfb;" | 23 || May 1 || @ Pirates || 5–2 || Musgrove (4–0) || Keller (0–4) || Rogers (9) || 8,350 || 15–8 || W1 |- style="background:#bbb;" | — || May 3 || @ Guardians || colspan=7| Postponed (rain); Makeup May 4 |- style="background:#bfb;" | 24 || May 4 || @ Guardians || 5–4 || Crismatt (1–0) || Plesac (1–3) || Rogers (10) || || 16–8 || W2 |- style="background:#fbb;" | 25 || May 4 || @ Guardians || 5–6 || Sandlin (2–1) || Lamet (0–1) || — || 10,244 || 16–9 || L1 |- style="background:#bfb;" | 26 || May 5 || Marlins || 2–1 || Martinez (2–2) || Luzardo (2–2) || Rogers (11) || 31,034 || 17–9 || W1 |- style="background:#bfb;" | 27 || May 6 || Marlins || 3–2 || Darvish (3–1) || Alcántara (2–2) || Wilson (1) || 37,585 || 18–9 || W2 |- style="background:#fbb;" | 28 || May 7 || Marlins || 0–8 || López (4–1) || Manaea (2–3) || — || 34,709 || 18–10 || L1 |- style="background:#bfb;" | 29 || May 8 || Marlins || 3–2 || Suárez (2–1) || Sulser (0–1) || — || 37,937 || 19–10 || W1 |- style="background:#fbb;" | 30 || May 9 || Cubs || 0–6 || Hendricks (2–3) || Gore (2–1) || — || 41,595 || 19–11 || L1 |- style="background:#bfb;" | 31 || May 10 || Cubs || 5–4 || Wilson (3–0) || Gsellman (0–1) || Rogers (12) || 31,047 || 20–11 || W1 |- style="background:#fbb;" | 32 || May 11 || Cubs || 5–7 || Givens (2–0) || García (0–2) || Wick (2) || 29,344 || 20–12 || L1 |- style="background:#bfb;" | 33 || May 13 || @ Braves || 11–6 || García (1–2) || Smith (0–1) || Rogers (13) || 40,635 || 21–12 || W1 |- style="background:#fbb;' | 34 || May 14 || @ Braves || 5–6 || Jansen (2–0) || Wilson (3–1) || — || 40,490 || 21–13 || L1 |- style="background:#bfb;" | 35 || May 15 || @ Braves || 7–3 || Crismatt (2–0) || Stephens (0–1) || — || 40,114 || 22–13 || W1 |- style="background:#bfb;" | 36 || May 17 || @ Phillies || 3–0 || Clevinger (1–0) || Eflin (1–3) || Rogers (14) || 29,200 || 23–13 || W2 |- style="background:#fbb;" | 37 || May 18 || @ Phillies || 0–3 || Wheeler (2–3) || Snell (0–1) || Knebel (8) || 27,655 || 23–14 || L1 |- style="background:#bfb;" | 38 || May 19 || @ Phillies || 2–0 || Darvish (4–1) || Gibson (3–2) || Rogers (15) || 30,146 || 24–14 || W1 |- style="background:#bfb;" | 39 || May 20 || @ Giants || 8–7 || García (2–2) || Doval (0–2) || Suárez (1) || 31,359 || 25–14 || W2 |- style="background:#bfb;" | 40 || May 21 || @ Giants || 2–1 || Musgrove (5–0) || Rodón (4–3) || Rogers (16) || 38,916 || 26–14 || W3 |- style="background:#bfb;" | 41 || May 22 || @ Giants || 10–1 || Gore (3–1) || Wood (3–3) || — || 35,363 || 27–14 || W4 |- style="background:#bfb;" | 42 || May 23 || Brewers || 3–2 || García (3–2) || Sánchez (0–1) || — || 31,504 || 28–14 || W5 |- style="background:#fbb;" | 43 || May 24 || Brewers || 1–4 || Burnes (2–2) || Snell (0–2) || Williams (3) || 39,834 || 28–15 || L1 |- style="background:#fbb;" | 44 || May 25 || Brewers || 1–2 || Perdomo (1–0) || Darvish (4–2) || Williams (4) || 27,831 || 28–16 || L2 |- style="background:#bfb;" | 45 || May 27 || Pirates || 4–3 || Crismatt (3–0) || Underwood Jr. (0–1) || Rogers (17) || 41,888 || 29–16 || W1 |- style="background:#fbb;" | 46 || May 28 || Pirates || 2–4 || Banda (1–0) || Rogers (0–1) || Bednar (9) || 38,189 || 29–17 || L1 |- style="background:#bfb;" | 47 || May 29 || Pirates || 4–2 || García (4–2) || Stratton (2–2) || — || 44,395 || 30–17 || W1 |- style="background:#fbb;" | 48 || May 30 || @ Cardinals || 3–6 || Pallante (1–0) || Martinez (2–3) || — || 42,140 || 30–18 || L1 |- style="background:#fbb;" | 49 || May 31 || @ Cardinals || 2–3 || VerHagen (3–0) || Rogers (0–2) || — || 33,418 || 30–19 || L2

|- style="background:#fbb;" | 50 || June 1 || @ Cardinals || 2–5 || Hudson (4–2) || Darvish (4–3) || Wittgren (1) || 34,268 || 30–20 || L3 |- style="background:#fbb;" | 51 || June 2 || @ Brewers || 4–5 || Strzelecki (1–0) || Rogers (0–3) || — || 21,451 || 30–21 || L4 |- style="background:#bfb;" | 52 || June 3 || @ Brewers || 7–0 || Musgrove (6–0) || Burnes (3–3) || — || 30,019 || 31–21 || W1 |- style="background:#bfb;" | 53 || June 4 || @ Brewers || 4–0 || Gore (4–1) || Ashby (1–4) || — || 37,376 || 32–21 || W2 |- style="background:#bfb;" | 54 || June 5 || @ Brewers || 6–4 || Hill (1–0) || Gott (1–1) || Rogers (18) || 32,285 || 33–21 || W3 |- style="background:#fbb;" | 55 || June 6 || Mets || 5–11 || Carrasco (7–1) || Snell (0–3) || — || 34,858 || 33–22 || L1 |- style="background:#bfb;" | 56 || June 7 || Mets || 7–0 || Darvish (5–3) || Walker (3–2) || — || 31,796 || 34–22 || W1 |- style="background:#bfb;" | 57 || June 8 || Mets || 13–2 || Manaea (3–3) || Bassitt (4–4) || — || 40,992 || 35–22 || W2 |- style="background:#bfb;" | 58 || June 10 || Rockies || 9–0 || Musgrove (7–0) || Kuhl (4–3) || — || 35,207 || 36–22 || W3 |- style="background:#bfb;" | 59 || June 11 || Rockies || 2–1 || Wilson (4–1) || Estévez (1–4) || — || 31,415 || 37–22 || W4 |- style="background:#fbb;" | 60 || June 11 || Rockies || 2–6 || Freeland (2–5) || Gore (4–2) || — || 30,040 || 37–23 || L1 |- style="background:#fbb;" | 61 || June 12 || Rockies || 2–4 || Márquez (3–5) || García (4–3) || Bard (13) || 41,754 || 37–24 || L2 |- style="background:#bfb;" | 62 || June 13 || @ Cubs || 4–1 || Darvish (6–3) || Wick (1–2) || Rogers (19) || 31,629 || 38–24 || W1 |- style="background:#bfb;" | 63 || June 14 || @ Cubs || 12–5 || Tyler (1–0) || Effross (1–2) || — || 29,233 || 39–24 || W2 |- style="background:#bfb;" | 64 || June 15 || @ Cubs || 19–5 || Stammen (1–0) || Kilian (0–1) || — || 31,570 || 40–24 || W3 |- style="background:#bfb;"