Maria Palaiologina () may refer to:
Maria Palaiologina (fl. 1265–1282), daughter of Emperor Michael VIII and Khatun of the Ilkhanate Maria Palaiologina Kantakouzene (fl. 1249–1294), niece of Emperor Michael VIII and Empress of Bulgaria Maria Palaiologina, Queen of Serbia (died 1355), great-granddaughter of Emperor Michael VIII Maria-Irene Palaiologina (1327–1399), Byzantine princess and Bulgarian empress consort Maria Palaiologina (Princess of Vereya) (died 1505), possibly a daughter of Andreas Palaiologos Mary Paleologus (died 1674), daughter of Theodore Paleologus