Mesostemma is a genus of flowering plants belonging to the family Caryophyllaceae. Its native range is from eastern Turkey to south-western Siberia and the Himalayas.

Species The following species are recognised in the genus Mesostemma: Mesostemma alexeenkoanum Mesostemma gypsophiloides Mesostemma karatavicum Mesostemma kotschyanum Mesostemma latifolium Mesostemma martjanovii Mesostemma perfoliatum Mesostemma platyphyllum Mesostemma schugnanicum

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