Santa Margarita, Spanish for Saint Margaret, may refer to:
Places United States Santa Margarita, California, a town in San Luis Obispo County Santa Margarita de Cortona Asistencia, an 18th-century mission near the town Santa Margarita Lake Rancho Santa Margarita, California, a city in Orange County Santa Margarita Catholic High School, in Rancho Santa Margarita Santa Margarita Formation, a geologic formation in the San Joaquin Valley, California Santa Margarita Mountains, San Diego County, California Santa Margarita River, in the Santa Ana Mountains, California
Other countries Santa Margarita Island, Magdalena Bay, Baja California Sur, Mexico Santa Margarita, Samar, Philippines Santa Margarita (La Línea de la Concepción), a gated community in the Province of Cadiz, Andalucia, Spain Santa Margarita, Trinidad and Tobago
Other uses Santa Margarita (shipwreck), a shipwreck near Key West off the coast of Florida, US Santa Margarita Stakes, an American Thoroughbred horse race at Santa Anita Park in California, US
See also Margarita (disambiguation) Saint Margaret (disambiguation) Santa Margalida, Mallorca, Spain Santa Margerita, Mosta, Malta Santa Margerita Chapel, in San Gwann, Malta Santa Margherita (disambiguation)