Pill is a surname. Notable people with the surname include:

Alison Pill (born 1985), Canadian actress Brett Pill (born 1984), American baseball player Cathy Pill (born 1981), Belgian fashion designer Huw Pill, British economist, chief economist of the Bank of England Malcolm Pill (born 1938), British judge Tyler Pill (born 1990), American baseball player Willow Pill (born 1995), American drag queen