Dubuque is a surname. Notable people with the surname include:
Alexandre Dubuque (1812–1898), French-Russian composer Bill Dubuque, American screenwriter Chuck Dubuque (1932–2020), Canadian football player Gene Dubuque (1927–1974), American wrestler Joe Dubuque (born 1982), American wrestler Julien Dubuque (1762–1810), French-Canadian, arrived near what is now Dubuque, Iowa