José de la Cruz may refer to:
José de la Cruz (writer) (1746–1829), Filipino writer José de la Cruz Sánchez (1749–1878), Californio statesman and ranchero José María de la Cruz (1799–1875), Chilean soldier José de la Cruz Porfirio Díaz Mor (1830–1915), better known as Porfirio Díaz, Mexican President José de la Cruz Mena (1874–1907), Nicaraguan composer José de la Cruz (footballer) (born 1952), Paraguayan football goalkeeper José Luis de la Cruz (born 2000), Dominican football right-back
See also Jose Cruz (disambiguation)