Potamon is a genus of freshwater or semiterrestrial crabs. Potamon may also refer to:
Potamon of Heraclea (died c. 341), a bishop of Heraclea in Egypt who was martyred Potamon of Mytilene (c. 65 BC–AD 25), a rhetorician in the Greek city of Mytilene Potamon (mythology), in Greek mythology an Egyptian prince, one of the sons of King Aegyptus Potamidae, a family of freshwater crabs