The 2021 NÖ Open was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Tulln an der Donau, Austria between 6 and 12 September 2021.

Singles main-draw entrants Seeds Country Player Rank1 SeedMarco Cecchinato811Jiří Veselý902Thiago Monteiro933Kamil Majchrzak1144Jozef Kovalík1185Damir Džumhur1206Dennis Novak1257Hugo Gaston1278 1 Rankings are as of 30 August 2021.

Other entrants The following players received wildcards into the singles main draw: Gerald Melzer Filip Misolic Lukas Neumayer

The following players received entry into the singles main draw as alternates: Johannes Härteis Lucas Miedler

The following players received entry from the qualifying draw: Benjamin Hassan Uladzimir Ignatik Matteo Martineau Neil Oberleitner

Champions Singles

Mats Moraing def. Hugo Gaston 6–2, 6–1.

Doubles

Dustin Brown / Andrea Vavassori def. Rafael Matos / Felipe Meligeni Alves 7–6(7–5), 6–1.

References