The women's 100 metres T53 event at the 2020 Summer Paralympics in Tokyo, took place on 1 September 2021.

Records Prior to the competition, the existing records were as follows:

Area Time Athlete Nation Africa 18.51 Olajumoke Annah Olajide America 16.23 Leann Shannon Asia 16.19 Huang Lisha Europe 16.21 Samantha Kinghorn Oceania 16.46 Angie Ballard

Results The final took place on 1 September 2021, at 20:37: Rank Lane Name Nationality Time Notes 3 Gao Fang 16.29 5 Zhou Hongzhuan 16.48 4 Samantha Kinghorn 16.53 4 7 Jessica Cooper Lewis 16.90 5 9 Hamide Doğangün 16.94 6 8 Catherine Debrunner 17.18 7 6 Angie Ballard 17.43 8 1 Kelsey Lefevour 17.56 9 2 Yen Hoang 18.01

References