General Payne may refer to:
Elisha Payne (1731–1807), Vermont Militia major general Frederick R. Payne Jr. (1911–2015), U.S. Marine Corps brigadier general Morris B. Payne (1885–1961), Connecticut National Guard major general William H. F. Payne (1830–1904), Confederate States Army brigadier general
See also Sir William Payne-Gallwey, 1st Baronet (1759–1831), British Army general General Paine (disambiguation)