Indagine (also ab Indagine, de Indagine) is a Latinized last name, derived from the Latin word for "investigation" or sign".
Notable people with the last name include:
Johannes de Indagine (Benedictine) (d. 1469), German Benedictine monk and abbot Johannes de Indagine (1415–1475), German monk and theologian Johannes Indagine (1467-1537), German humanist and priest
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