Camila Giorgi defeated Karolína Plíšková in the final, 6–3, 7–5 to win the women's singles tennis title at the 2021 Canadian Open. It was her third career WTA Tour title, her first at the WTA 1000 level, and her first since Linz in 2018.

Bianca Andreescu was the defending champion from when the event was last held in 2019, but lost in the third round to Ons Jabeur.

Seeds The top eight seeds received a bye into the second round.

Draw

Finals

Top half

Section 1

Section 2

Bottom half

Section 3

Section 4

Qualifying

Seeds

Qualifiers

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

Seventh qualifier

Eighth qualifier

References

External links Main draw Qualifying draw