Hemisinidae is a family of snails in the superfamily Cerithioidea. They occur in freshwater and brackish environments on all continents except Australia and Antarctica.

Genera There are five extant genera: Aylacostoma Spix, 1827 Cubaedomus Thiele, 1928 Hemisinus Swainson, 1840 Longiverena Pilsbry & Olsson, 1935 Pachymelania E. A. Smith, 1893

There are also four genera only known from fossils: † Axonella Pacaud, Lhomme & Renaud, 2021 † Gantmelania Kowalke, 2001 † Pyrgulifera Meek, 1871 † Stephaniphera S. Schneider, Kollmann & Pickford, 2020

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