Leiser is a surname. Notable people with the surname include:
Alfred Leiser (born 1929), Swiss racewalker Brian Leiser (better known as Fast, born 1972), American musician Clara Leiser (c. 1898–1991), American writer, journalist, and activist David Leiser (born 1952), Israeli professor of psychology Eric Leiser, American filmmaker, animator and holographer Ernest Leiser (1921–2002), American executive producer and journalist Erwin Leiser (1923–1996), German Jew, director, writer and actor Jacques Leiser, American artists manager and photographer Louis G. Leiser (1927–2009), American major general in the United States Air Force Martin Leiser (born 1978), Swiss athlete Vreni Leiser (born 1945), Swiss sprinter Walter Leiser (1931–2023), Swiss rower
See also Leiser Madanes (born 1950), Argentine writer, philosopher and professor Moshe Leiser and Patrice Caurier, Opera directors