Ghana competed at the 2019 World Championships in Athletics in Doha, Qatar, from 27 September–6 October 2019.
Results (q – qualified, NM – no mark, SB – season best)
Men Track and road events AthleteEventPreliminaryHeatSemi-finalFinalResultRankResultRankResultRankResultRank Joseph Paul Amoah 100 metrescolspan=210.3634colspan=4 Sean Safo-AntwiBenjamin Azamati-KwakuMartin Owusu AntwiJoseph Paul Amoah 4 × 100 metres relaycolspan=238.24 13colspan=2colspan=2
Women Track and road events AthleteEventHeatSemi-finalFinalResultRankResultRankResultRank Flings Owusu-AgyapongGemma AcheampongPersis William-MensahHalutie Hor 4 × 100 metres relay43.62 11colspan=2colspan=2
References