Sant'Elena may refer to:
Sant'Elena (island), an island of Venice, Italy Sant'Elena, Rome, a church in Rome, Italy Sant'Elena, Venice, a Gothic-style, Roman Catholic church in Venice, Italy. Sant'Elena, Veneto, a comune in the Province of Padua in the Italian region Veneto, Italy Sant'Elena Sannita, a comune in the Province of Isernia in the Italian region Molise, Italy
See also Santa Elena (disambiguation)