Root sheath may refer to any of these biological structures:
Epithelial root sheath, a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth Root sheath (hair), the inner or epidermic coat of the hair follicle that is closely adherent to the root of the hair Inner root sheath Outer root sheath Seed root sheath, a protective layer of tissue that surrounds the radicle in monocotyledon seeds