3',4'-Methylenedioxy-4-methylaminorex (MDMAR) is a recreational designer drug from the substituted aminorex family, with monoamine-releasing effects. It is a potent serotonin–norepinephrine–dopamine releasing agent (SNDRA).
+ Compound Ref Phenethylamine 10.9 39.5 >10,000 Dextroamphetamine 6.6–10.2 5.8–24.8 698–1,765 Dextromethamphetamine 12.3–14.3 8.5–40.4 736–1,292 Aminorex 15.1–26.4 9.1–49.4 193–414 cis-4-MAR 4.8 1.7 53.2 cis-4,4'-DMAR 11.8–31.6 8.6–24.4 17.7–59.9 trans-4,4'-DMAR 31.6 24.4 59.9 cis-MDMAR 14.8 10.2 43.9 trans-MDMAR 38.9 36.2 73.4 Notes: The smaller the value, the more strongly the drug releases the neurotransmitter. The assays were done in rat brain synaptosomes and human potencies may be different. See also Monoamine releasing agent § Activity profiles for a larger table with more compounds. Refs:
See also Substituted methylenedioxyphenethylamine 2C-B-aminorex 4B-MAR 4C-MAR 4,4'-DMAR 4'-Fluoro-4-methylaminorex 5-MAPB MDMA Methylenedioxyphenmetrazine List of aminorex analogues
References