Grueso is a surname. Notable people with the surname include:
Antonio Latorre Grueso, Spanish footballer Daniel Grueso (born 1985), Colombian sprinter Gustavo Adolfo Torres Grueso (born 1996), Colombian footballer Libia Grueso, Colombian social worker and civil rights activist Roberto Carlos Peña Grueso (born 1984), Colombian footballer
See also Gruezo: Carlos Gruezo (footballer, born 1975), Ecuadorian footballer Carlos Gruezo (footballer, born 1995), Ecuadorian footballer