Große or Grosse is a German surname. Notable people with the surname include:
Aristid von Grosse (1905–1985), German nuclear chemist Ben Grosse, American record producer and mixer Carl Grosse (1768–1847), German author, translator, philosopher, and mineralogist Catrin G. Grosse (born 1964), German painter, graphic designer and sculptor Charles le Grosse (c. 1596–1650), English politician Christina Große (born 1970), German actress Demetrius Grosse (born 1981), American actor and producer Doris Große (born 1884), German artists' model for Ernst Ludwig Kirchner Fritz Große (1904–1957), German politician and diplomat George Grosse (1930–2016), American politician from Florida Hans-Werner Grosse (1922–2021), German bomber pilot Heinz-Josef Große (1947–1982), East German construction worker Johannes Große (born 1997), German field hockey player Julius Grosse (1828–1902), German poet Katharina Grosse (born 1961), German visual artist Maurice Grosse (1919–2006), British paranormal investigator Nina Grosse (born 1958), German film director and screenwriter Steffen Grosse (born 1967), German politician Theodor Grosse (1829–1891), German historical painter Twila Grosse, Canadian politician Ulrich Grosse (born 1953), German public transport consultant