The 2021 NCAA Division I Women's Lacrosse Championship was the 39th annual single-elimination tournament to determine the national champion of Division I NCAA women's college lacrosse. The semifinal and championship rounds were played at Johnny Unitas Stadium in Towson, MD from May 28–30, 2021. All other rounds were played at campus sites, usually at the home field of the higher-seeded team, from May 14–22. This was the first NCAA tournament since the 2019 NCAA tournament after the 2020 edition was cancelled due to the COVID-19 pandemic.

Tournament field All NCAA Division I women's lacrosse programs were eligible for this championship, and a total of 29 teams were invited to participate. 15 teams qualified automatically by winning their conference tournaments while the remaining 14 teams qualified at-large based on their regular season records.

Teams Seed School Conference Berth Type RPI Record1 North Carolina ACC Automatic118–02 Northwestern Big Ten Automatic713–03 Syracuse ACC At-large214–34 Boston College ACC At-large313–35 Notre Dame ACC At-large69–66 Florida American Automatic1016–27 Duke ACC At-large219–78 Stony Brook America East Automatic514–2 UConn Big East At-large3012–6 Denver Big East Automatic1314–3 Drexel CAA At-large413–2 Fairfield MAAC Automatic1413–1 High Point Big South Automatic3810–7 Hofstra CAA At-large116–6 Jacksonville ASUN Automatic1711–1 James Madison CAA Automatic1511–4 Johns Hopkins Big Ten At-large468–6 Loyola (MD) Patriot Automatic811–2 Maryland Big Ten At-large369–6 Massachusetts Atlantic 10 Automatic1215–2 Mercer SoCon Automatic457–7 Mount St. Mary's NEC Automatic1614–2 Robert Morris MAC Automatic3914–2 Rutgers Big Ten At-large546–8 Stanford Pac-12 Automatic911–0 Temple American At-large1812–5 Towson CAA At-large239–8 Vanderbilt American At-large1912–6 Virginia ACC At-large258–8

Bracket

Tournament bracket Games on Conference Sports Networks (BTN & BTN+) or ESPN3 for First & Second Rounds. Semifinals on ESPNews & Finals on ESPNU.

*First and second round host.

See also NCAA Division II Women's Lacrosse Championship NCAA Division III Women's Lacrosse Championship NCAA Division I Men's Lacrosse Championship

References

Copied content from 2019 NCAA Division I Women's Lacrosse Championship; see that page's history for attribution