Gene is a unisex given name. It is often a short form (hypocorism) of Eugene or Genevieve.

Notable people with the name include:

Men Gene Gene Abel, American psychiatrist and controversial clinician Gene Bradley (born 1957), American football player Gene Charron (born 1942), American politician Gene A. Cretz (born 1950), American politician Gene Davidson (1896–1960), American football and baseball player Gene Englund (1917–1995), American professional basketball player Gene F. Franklin (1927–2012), American engineer and control theorist Gene Makowsky (born 1973), Canadian Football League player and politician Gene Miles (born 1959), Australian rugby league footballer Gene Moore (window dresser) (1910–1998), American designer and store window dresser Gene Noble, American singer and songwriter Gene Pitney (1940–2006), American singer-songwriter Gene Rayburn (1917–1999), American radio and television personality Gene Robillard (1929–2007), Canadian football player Gene Sarazen (1902–1999), American golfer Gene Simmons (born 1949), Israeli-American musician, singer, and songwriter Gene Smith (athletic director), athletic director at Ohio State University Gene Spafford (born 1956), American computer scientist and cybersecurity pioneer Gene Steratore (born 1963), former American football official in the National Football League Gene Ween (born 1970), American musician Gene Weingarten (born 1951), American humor writer and journalist Gene Wilder (1933–2016), American actor and comedian Gene Wolfe (1931–2019), American science fiction author

Eugene Gene Cockrell (1934–2020), American football player Gene Filipski (1931–1994), American football player Gene Gotti (born 1946), Italian-American mobster Gene Hackman (1930–2025), American actor Gene Kelly (1912–1996), American dancer and film star Gene Kranz (born 1933), American aerospace engineer and NASA Flight Director and manager Gene Mangan (1936–2025), Irish cyclist Gene Moore (outfielder) (1909–1978), right fielder in Major League Baseball Gene Moore (pitcher) (1886–1938), left-handed pitcher in Major League Baseball Gene Moore (basketball) (born 1945), American Basketball Association player Gene Okerlund (1942–2019), American professional wrestling announcer Gene Prebola (1938–2021), American football player Gene Quaw, (1891–1968), American musician Gene Quill (1927–1988), American jazz alto saxophonist Gene Quintano (born 1946), American screenwriter, actor, producer, and director Gene Roddenberry, (1921–1991), American television screenwriter and producer Gene Samuel (born 1960), Trinidad and Tobago road bicycle racer and track cyclist Gene Siskel (1946–1999), American film critic Gene Snitsky (born 1970), American professional wrestler Gene Sobchuk (born 1951), Canadian ice hockey player Gene Stuart, (1944–2016), Irish singer Gene Upshaw (1945–2008), American National Football League (NFL) player and former NFL Players Association director

Women Gene Gene Anderson (actress) (1931–1965), English actress Gene Cohen Boyer (1925–2003), American women's rights activist Gene Bradford (1909–1937), American politician Gene Damon (1933–2011), American writer and publisher Gene Derwood (1909–1954), American poet and painter Gene Field Foster (1917–1983), American carpenter, artist, anthropologist, ornithologist, and early Glen Canyon river runner Genė Galinytė (born 1945), Lithuanian rower Gene Grabeel (1920–2015), American mathematician and cryptanalyst Gene Hatch, American businesswoman Gene Nora Jessen (1937–2024), American aviator and a member of Mercury 13 Gene Joseph, is a Wet'suwet'en Nadleh'dena First Nations librarian from Nagwilget, British Columbia Gene Kemp (1926–2015), English author Eugenia Kennicott (1883–1934), recorded her life in Colorado in early 19th century in rare photographic plates Gene Kloss (1903–1996), American artist Gene Miles (activist) (1930–1972), political activist from Trinidad and Tobago Gene E. K. Pratter (1949–2024), American judge Gene Sherman (art specialist) (born 1947), philanthropist, academic and expert on art, fashion and architecture Gene Solia-Gibb (born 1983), Samoan New Zealand netball and rugby player Gene Stratton-Porter (1863–1924), American writer, nature photographer, and naturalist Gene Tierney (1920–1991), American actress Gene Weltfish (1902–1980), American anthropologist and historian

Genevieve Genevieve Grotjan Feinstein (1913–2006), American mathematician and cryptanalyst Gene Gauntier (1885–1966), American screenwriter and actress Genevieve George (1927–2002), Canadian baseball player Genevieve or Gene Lynch (1891–1960), American painter and art teacher Gene Ritchie Monahan (1908–1994), American portrait and landscape artist Genevieve or Gene Roberts (1926–2018), stage name Meg Randall, American actress Gene Segerblom (1918–2013), American politician Gene Visich (1926–2012), American baseball player

See also Gene (disambiguation) Jean (disambiguation) Gene-Ann Polk (1926–2015), American physician and hospital administrator and professor of pediatrics