The Omisore family () is a noble Yoruba family originating from Ife, Nigeria. The Omisore family was founded by the aristocratic chief of Ife, Lowa Ajani Anibijuwon Omisore.

Etymology The surname is a reference to the Yoruba river goddess, Oshun. It is a contraction of the Yoruba phrase "Omi-ṣe-mí-lore", meaning "water has done good things for me". The surname has also been translated to "water has done good deeds" or "water has done us Favour".

People Iyiola Omisore – Nigerian engineer, businessman, politician, and former senator of Osun State Ajani Anibijuwon Omisore – Chief and Lowa of Ife Dot da Genius (Oladipo Omisore) – music producer, audio engineer, and electrical engineer Dotun Omisore - Chemical Engineer Chief Adetunji Omisore - Lawyer, Business mogul, Grandson of Oba Adesoji Aderemi Kaziah Moradeke Milner nee Omisore - Hollywood Actress, Model, Business Mogul, Great Granddaughter of Oba Adesoji Aderemi

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